Official announcement (January 1st 2005)
Dear Friends and Colleagues,
We are happy to announce Biozon (http://biozon.org/) - a new
knowledge resource of heterogeneous biological data.
Biozon integrates published data on DNA sequences, protein sequences,
protein structures, protein-protein interactions, cellular pathways
and protein families derived from sources such as PDB, Genbank,
Uniprot, KEGG, and BIND.
Biozon augments this data with in-house derived data such as sequence
or structure similarity, predicted interactions, and predicted
domains. Biozon data sets include (among others)
~38 Million nucleic acid sequences
~1.8 Million protein sequences
~28,000 protein structures
~73,000 interactions
~2.25 Billion sequence alignments
~8 Million structural alignments
The complete statistics is available at
http://biozon.org/doc/statistics.html
This a pre-release, preceding the official release scheduled for
January, 2005. This release introduces many new features for the
first time. As such, it is considered beta and is still undergoing
evaluation and testing. We ask for your observations, comments, or
questions to help it continue to evolve into something truly useful.
Currently, the following features are available for public use:
- View each biological entity in its extended biological
context, through its relations to other biological
entities.
- Complex searches on the data graph that specify desired
interrelationships between types (e.g. searches like '3D
structures of proteins that are involved in
phosphorylation interactions and are part of the
Prostaglandin and leukotriene metabolism pathway').
- First-of-a-kind biological ranking system which
resembles the methods implemented in Google.
- Fuzzy searches that extend complex searches to include
homologous sequences or structures as a search step.
- Analysis tools such as domain prediction, structure and
sequence similarity and analysis of expression data.
- Account management system that enables users to save
queries and materialize data from search results to
download for further analysis or include as a step in some
other complex query.
- Graphical visualization of domains, GO terms, protein
structures, structural alignments and interaction maps.
You are invited to preview Biozon. We hope you will find
it useful. Feedback will be most appreciated.
Golan Yona
The Biozon Team
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